Background: | The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses. Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. |
Applications: | ELISA, WB, IHC |
Name of antibody: | TRAFD1 |
Immunogen: | Fusion protein of human TRAFD1 |
Full name: | TRAF-type zinc finger domain containing 1 |
Synonyms: | FLN29 |
SwissProt: | O14545 |
ELISA Recommended dilution: | 1000-2000 |
IHC positive control: | Human thyroid cancer and human brain |
IHC Recommend dilution: | 25-100 |
WB Predicted band size: | 65 kDa |
WB Positive control: | Mouse spleen tissue |
WB Recommended dilution: | 200-1000 |